N Fowleri Nf Nf1, supplied by ATCC, used in various techniques. List your CBD store. Find information about the NF1 Ready To Roll strain from Old Pal such as potency, common effects, and where to find it. time (sec) spent sniffing cotton swabs dipped in each respective scent during a 2 min. Andersson, Elizabeth Blears, Maria José Figueras, Nur A. Get details and read the latest customer reviews about NF-1 by UpNorth Humboldt on Leafly. Hasan, Rita R. NF_NF1 strain which bene ts from the compilatio n of 5 . Indica dom on mine. Shop Nf1. Red Velvet is a unknown variety from Lit Farms and can be cultivated indoors (where the plants will need a flowering time of ±60 days) and outdoors. and its expression was increased 6. Progress over the past 3 years has included the generation of three mouse models of NF1. Find information about the NF-1 Live Resin Budder from UpNorth Humboldt such as potency, common effects, and where to find it. Strain Gene Model ID Feature Type. Check availability for NF-1. All. He began moving flowers in his youth in Santa Barbara, near Figueroa Mountain. Share. Mimosa’s popularity has been steadily growing since its arrival on the cannabis scene in 2017. J:217077 De Raedt T, et al. Prefers moderate amounts of fertilizer. Neurofibromatosis Type 1 (NF1) is a common genetic disorder and cancer predisposition syndrome (1:3000 births) caused by mutations in the tumor suppressor gene NF1. In the literature this association has been described in. No promise that’s what’s still in the jar by the time you get it. . congenic, targeted mutation MGI ID. Phone. Diagnostic criteria are varied and include café-au-lait spots, neurofibromas, freckling of the axillary or inguinal regions, optic glioma, Lisch nodules, distinctive osseous lesions (such as sphenoid dysplasia or thinning of long bone cortex),. fo wleri genome . B6. F1 is a super rare sativa dominant hybrid strain (70% sativa/30% indica) created through an unknown combination of other sativa heavy strains. I still love the Durban for its Nose and mental clarity but this NF-1 is my preferred cultivar. This is not the strain to consume when you have a long list of errands that you have to complete in a timely manner. Mimosa, also known as "Purple Mimosa," is a hybrid marijuana strain made by crossing Clementine with Purple Punch. Mitochondrial. Nitrogen Dependent,. Get details and read the latest customer reviews about NF-1 by UpNorth Humboldt on Leafly. Nf1+/– mice were obtained from Tyler Jacks at the Massachusetts Institute of Technology (Cambridge, Massachusetts, USA) in a C57BL/6J. 5 (Figure 2) (Mann-Whitney, Wt vs. Delivery Stores Deals Strains Products Doctors Cannabis 101 Social impact. It is caused by mutations in the NF1 tumor suppressor gene, which encodes a GTPase. Hey bud, the strain Nf1 is new to us and we're still gathering information about it. 0 stars. This cannabis seed strain is a great choice for tackling the symptoms of mood disorders like depression and bi-polar disorder, and can ease stress and anxiety. Stress. Stress. An earlier report described a human case of necrotizing fasciitis (NF) caused by mixed infection with 4 Aeromonas hydrophila strains (NF1-NF4). Ive had bud like this good but nothing special to me. 14% of people say it helps with Stress. Visible neurofibromas add significant psychosocial. In small doses, this strain produces happy, level-headed effects that will leave. This study aimed to elucidate the un. With earthy flavors of lemons and citrus, Amnesia Haze is the perfect sativa strain to start your day with a smile. Shop legal, local weed. The central element of this model is the regulatory feedback loop between tissue strain and bone. Love this strain Upnorth is great stuff and I’ve bought it many times over but I got one and it was all one bud. But. In an effort to identify potential sleep disturbances in a small animal model, we used a previously reported Nf1 conditional knockout (Nf1 CKO ) mouse strain. NF1 (a cross between Northern Lights and Chemdawg) is perfect for all-day enjoyment and day-time activities. If you've smoked or otherwise consumed this strain, please leave a review. calming energizing. Posted on March 30, 2023 by Michael Lasley March 30, 2023. lovaniensis (NL_Lova7, green) if they belong to the core-genome. Although Nf1 +/− mutant mice do not develop the benign lesions commonly seen in human NF1, such as neurofibromas and optic gliomas, Nf1 and Trp53 compound heterozygotes on a mixed C57BL/6×129S4. Isolates NF1 to NF4 were from a patient with. Signs are often noticeable at birth or shortly afterward and almost always by age 10. The human disease von Recklinghausen's neurofibromatosis (Nf1) is one of the most common genetic disorders. Delivery Dispensaries Deals Strains Brands. 2 In 2007, an NF1. NF1 is a potent Sativa-dominant strain which is very popular among our budtenders here at Holyoke Cannabis Recreational Dispensary. We're still learning about the flavors and effects of NF1. 5C), only NF1 strains were detected and the average bacterial counts were 1. An earlier report described a human case of necrotizing fasciitis (NF) caused by mixed infection with 4 Aeromonas hydrophila strains (NF1-NF4). When the strains occur together, the story is reversed. While the NF2, NF3, and NF4 strains were clonal and possessed exotoxin A (ExoA), the NF1 strain was determined to be phylogenetically distinct, harboring a unique type 6 secretion system (T6SS. Anxiety. Sour Tsunami is a strain that became famous for being one of the first to be specifically bred for high CBD rather than THC content. When they swapped the genetic components that varied between the strains, the team was able to make NF1 behave more like NF2 and vice versa. 1998). Using a large number of Bradyrhizobium strains, this study shows that the ability to nodulate A. A cytological characterization of the parasitic action of ultramicrobacteria NF1 and NF3 of the genus Kaistia on chemoorganotrophic and phototrophic bacteria . Delivery Dispensaries Deals Strains Products CBD Doctors Cannabis 101 Social impact. Thus, sharing similar proteins of the type IV secretion system could favour HGT among strains responsible for CBB. This latter strain has the Nf1 gene knocked out in the entire limb, including the myofibers, adipocytes and vascular cells, yet the mice survive as previously reported . A limb-specific Nf1 knockout mouse (Nf1 Prx1-/-) was generated using a Prx1-cre transgene to drive deletion of Nf1 in cells of the mesenchymal lineage in the fore and hind limbs. Upnorth is a Humboldt growers collective focusing on high quality indoor flower grown sustainably and with intent. NF2-P1 and NF1 strains collected from Newfoundland were found in Clade 2 but were also occasionally assigned to Clades 1 or 5. 9. Pharmaceutical compositions and functional food compositions comprising the nano-sized L. Search. This progeny is heavy on the THC, heavy on the indica, and heavy on […]Ghost Train Haze is a suitable outdoor strain, good for growing in warm climates. Sort by. Lemon Thai produces high yields both indoors and outdoors but appreciates a lot of space to grow. It is very crystallized & the smell is definitely there! Haven’t tried it yet will post after! Any comments feel free! This is absolutely one of the most underrated strains of last year, no question. “NF1” is a cross between TWO all-time classics “Chemdog” and “Northern Lights” that have gained major popularity through their time in existence. Neurofibromin is a 320-kDa Ras-specific GTPase activating protein (RasGAP) that uses the central GAP-related domain (GRD) to enhance the GTPase activity of the small guanine nucleotide binding protein Ras, thereby down-regulating its biological activity (3–5). To date, few genotype-phenotype correlations have been discerned in NF1, due to a highly variable clinical presentation. Durban is always very high in terps and has such a good high to it. NF1 is a gene that encodes the neurofibromin 1 protein, an inhibitor of RAS that works through GTPase activity (Kiuru and Busam, 2017). To date, models of NF2-associated ependymoma remain yet to be generated whereas genetically engineered mouse strain of. The data presented in this paper demonstrate that strain background has as much effect on Nf1 expression levels as mutation of one Nf1 allele, indicating that studies of haploinsufficiency must be carefully interpreted. AK Auto-Flowering Cannabis Seeds. “NF1” is said to have dense, tight buds that give off a powerful gassy aroma with a hint of earthinessStrain Name: C57BL/6JGpt-Nf1 em1Cflox /Gpt: Strain Number: T007997: Official Symbol: Nf1: Strain Strategy: T007997. The NF1 gene has gained considerable impact as it is frequently mutated in a variety of very. NF1 is a hybrid marijuana strain with talkative, energetic and focused effects. Had their Wedding Mints. 0 μm. In their development cycle, the strains formed small coccoid cells of 400–800 nm and. Recently, mutations in the neurofibromin 1 (NF1) tumor suppressor gene were identified in multiple subtypes of human soft-tissue sarcomas. AllBud. My expertises. An international team including University of Maryland scientists revealed how genetic variations in a single sp THC: 25% - 26%. Locating. 017639 STOCK Nf1 tm1Par /J These Nf1 flox mice possess loxP sites flanking exons 31-32 of the neurofibromatosis 1 gene ( Nf1 ), and have applications in studying cancer, neural crest development and neurofibromatosis type I. 3% Delta-9-THC, 23. There are three types of NF: NF1 accounting for 96% of all cases, NF2 in 3%, and schwannomatosis (SWN) in <1%. (A,B) Gross dissection (A) and H&E staining (B). While the NF2, NF3, and NF4 strains were clonal and possessed exotoxin A (ExoA), the NF1 strain was determined to be phylogenetically distinct, harboring a unique type 6 secretion system (T6SS) effector. Buy strains with similar effects to. An earlier report described a human case of necrotizing fasciitis (NF) caused by mixed infection with 4 Aeromonas hydrophila strains (NF1–NF4). NF1. 8-fold when com-pared to the wild-type strain BY4742. NF1 patients showed lower Z-scores at Dual-Energy X-ray Absorptiometry DXA than controls. (A) In the circos plot, protein coding genes of N. This mouse strain has reduced muscle weight, muscle weakness, fibrosis and impaired myoblast differentiation in the developing limbs . The high has a subtle build of. An earlier report described a human case of necrotizing fasciitis (NF) caused by mixed infection with 4 Aeromonas hydrophila strains (NF1–NF4). An earlier report described a human case of necrotizing fasciitis (NF) caused by mixed infection with 4 Aeromonas hydrophila strains (NF1–NF4). Plant AK Auto-Flowering indoors or out. Log in. Approximately 50% of NF1 mutations are sporadic (). NF1 Strain. Best indoors and in sunny climates. Find out everything you want to know about the marijuana strain Nf1. Please click and read the info below before making your first pre-order. NF1 strain is a rare and powerful hybrid (80% indica/20% sativa) that combines the piney scent of Northern Lights with the diesel aroma of Chemdawg. 027678 B6;129- Trp53 tm1Tyj Nf1 tm1Tyj Suz12 Gt(Betageo)1Khe /KcichJ These NPS+/- mice carry Trp53 , Nf1 , and Suz12 mutations on chromosome 11 (in cis) and develop high-grade gliomas and malignant peripheral nerve sheath tumors by approximately 3. Comfortable and easygoing high. Description. Delivery Dispensaries Deals Strains Brands Products CBD Doctors Cannabis. 63% of the total weight with terpinolene, limonene, β-caryophyllene, and β-myrcene being the heaviest. Many NF1 patients have been genotyped but few allele-phenotype correlations have been identified. The NF1 strain is one that you might have never heard of before. People report a range of effects from NF1, but most often report feeling immediately creative, energetic enough to tackle the day, giggly, and relaxed. NF-1 is an indica-leaning hybrid cross of Northern Lights and Chemdawg. Find information about the NF-1 Live Resin Sugar from UpNorth Humboldt such as potency, common effects, and where to find it. The high has a subtle build of effects, sneaking into the brain slowly before lifting the spirits into a. , 2002) that targets Cre-mediated recombination only in astrocytes of the retina (see Fig. People know little about its genetics or history. Chemdawg is a legendary strain with an uncertain genetic history. Tomato cages were used to restrict lower growth. A salt-tolerant denitrifying bacterium F1 was isolated in this study, which has high nitrite (NO2−–N) and nitrate (NO3−–N) removal abilities. THC: 20%. Insufficient data and resources represent major challenges to identifying the best possible drug therapies for children. The condition is usually recognized in early childhood, when pigmentary manifestations emerge. Jokerz effects are believed to be more relaxing than energizing. Not all people with NF1 inherit the disease. Therefore, m00100580b was closer between NF1 strains and other strains from group 9. The effects wrap you. Terpenes. Anxiety. IDs. Pharmaceutical compositions and functional food compositions comprising the nano-sized L. This mouse strain has reduced muscle weight, muscle weakness, fibrosis and impaired myoblast differentiation in the developing limbs . NF1 is a rare indica dominant hybrid strain (80% indica/20% sativa) created through crossing the classic Northern Lights X Chemdawg strains. In multi-strain infections, the toxin produced by NF2 breaks down the muscle tissue and enables NF1 to travel to the bloodstream or organs. 13%. A lot of sativas exacerbate my anxiety but the J1 gives me the perfect calming buzz. MRI scans, pathology records) you must send us beforehand. About half of people with NF1 have plexiform neurofibromas, but most are internal and not suspected clinically. trial. While the NF2, NF3, and NF4 strains were clonal and possessed exotoxin A (ExoA), the NF1 strain was determined to be phylogenetically distinct, harboring a unique type 6 secretion system (T6SS. Background. 0. Ana Fernández-Bravo, Paul B. Commonwealth Alternative Care created the NF1. com provides patients with medical marijuana strain details as well as marijuana dispensary and doctor review information. . 71 / gram) Listed THC 28. Get details and read the latest customer reviews about NF-1 by Northern Emeralds on Leafly. A strain specific cannabis extract. If you've smoked this strain before, tell us about it by leaving a review. This latter strain has the Nf1 gene knocked out in the entire limb, including the myofibers, adipocytes and vascular cells, yet the mice survive as previously reported . Parental bioluminescent NF2-lux strain was 1:1 mixed with parental or various. This is old school high. NF1 (aka NF-1) is a hybrid marijuana strain. Purchased 02/12/21 from Harborside. . Opens in new window. MAC, also known as "Miracle Alien Cookies" or simply "Miracle Cookies," is a hybrid marijuana strain made by crossing Alien Cookies with Starfighter and Columbian. We're still learning about the flavors and effects of NF1. In an earlier study, we reported infection of an immunocompetent individual with multiple strains of Aeromonas hydrophila (NF1-NF4), the latter three constituted a clonal group whereas NF1 was phylogenetically distinct. We're still learning about the flavors and effects of NF1. 78/10 overall a good even highUpNorth - NF1. An earlier report described a human case of necrotizing fasciitis (NF) caused by mixed infection with 4 Aeromonas hydrophila strains (NF1–NF4). Neurofibromatosis (NF) is a neurocutaneous syndrome characterized by the development of tumors of the central or peripheral nervous system including the brain, spinal cord, organs, skin, and bones. Set your location. Neurofibromatosis 1 (NF1), historically called von Recklinghausen’s disease, is a genetic disorder characterized by increased risk of developing noncancerous (benign) and cancerous (malignant) tumors, as well as various other physical and neurological manifestations. Arg1809Cys NF1 mutation 40 was engineered in mice on a C57Bl/6J background by CRISPR/Cas9. In addition, we obtained mature muscle tissue from Nf1 Prx1 −/− mice. The Gelato 33 weed strain is a specially formulated Gelato strain phenotype with strong savory flavors and potent effects. Strane STASH oil cartridges are made. NF1 (aka NF-1) is a hybrid marijuana strain. indica via a NF-independent, T3SS-independent process is restricted to Bradyrhizobium strains. F1 is a super rare sativa dominant hybrid strain (70% sativa/30% indica) created through an unknown combination of other sativa heavy strains. The effects of Frosty are more calming than energizing. Preliminary anchoring of scaffolds using a 37 pseudo-molecules reference (NF_TY) during the assembly process, genes can be positioned onto 37 newly. Finding a. 19% of people say it helps with Depression. Mitochondrial. Patients also find AK useful for calming headaches and inducing sleep. Get details and read the latest customer reviews about Dionysus by One on Leafly. Lit Farms' Red Velvet is a THC dominant variety and is/was only available as feminized seeds. Very salty/peppery in smell and smoke flavor. The high has a subtle build of effects, sneaking into the brain slowly before lifting the spirits into a. CommonwealthTHC: 23% - 24%. plantarum) nF1 strain isolated from kimchi and which has a particle size distribution of 0. This strain brings together the piney and diesel aromas from it's classic heritage. Terpenes were 1. NF1 is a cross of the classic Northern Lights and Chemdawg strains. 1 / 4. Today we check out NF-1 from UpNorth. , Tumour predisposition in mice heterozygous for a targeted mutation in Nf1. Arg1809 and a single amino acid. NF1 is a Sativa with some very well-known parents—Northern Lights and Chemdawg. Malignant tumors and other cancers associated with neurofibromatosis are treated with standard cancer therapies, such as surgery, chemotherapy and radiation therapy. . . An earlier report described a human case of necrotizing fasciitis (NF) caused by mixed infection with 4 Aeromonas hydrophila strains (NF1–NF4). NF1 mutation selectively disrupts social learning/memory which is rescued by p21-activated kinase 1 (Pak1) Description: Neurofibromatosis type 1 (NF1) is a common neurocutaneous. Okay this is the bud that actually made me start to want to write some more reviews after a long break. Certify your lab. Neurofibromatosis type 1 (NF1), a common genetic disorder with a birth incidence of 1:2,000-3,000, is characterized by a highly variable clinical presentation. Category: Flower. Grabbed this a month ago. calming energizing. Opens in new window. However, whether life has both stable genomes and extremely diverse genomes at the same time is unknown. Products. Neurofibromatosis Type 1 (NF1) is a genetic neurocutaneous disorder with multisystem manifestations, including a predisposition to tumor formation and bone dysplasias. NF1 is a hybrid cannabis strain. Although NF1 is associated with marked clinical variability, most children affected follow patterns of growth and development. Bred by Cookie Fam Genetics, Gelato. 129S2-Nf1 tm1Tyj /J Attributes. About half of people with NF1 have plexiform neurofibromas, but most are internal and not suspected clinically. Blue Razz [12oz] (10mg) Keef. Three forms of NF Type 1, NF Type 2 and Schwannomatosis are very different, but they all result in the growth of slow growing but still painful, dangerous, potentially life threatening tumors. The salt tolerance of strain F2 was ver. The condition is usually recognized in early childhood, when pigmentary manifestations emerge. 19% of people say it helps with Depression. Neurofibromatosis type 1 (NF1), one of the most common autosomal dominant genetic disorders, is caused by mutations in the NF1 gene. coli NEO6) of E. I feel robust stone way more than the transparent one that the Durban has. In multi-strain infections, the toxin produced by NF2 breaks down the muscle tissue and enables NF1 to travel to the bloodstream or organs. The recombinant strains B×D38, B×D39, and B×D40 exhibit a trend for higher levels of Nf1 expression than the other background strains, further suggesting that Nf1 expression is variable among different background strains and between different tissues within the strain. 80% Sativa, 20% Indica Growth. THC levels up to 18%. See More Marijuana Strains. With those admired genetics crossed UpNorth brings you NF1: a very strong hybrid sativa dominant strain. JAX:008192 Associated. 5 to 1. The strain is quite popular amongst new and experienced cannabis users alike. (A) In the circos plot, protein coding genes of N. Global longitudinal strain might be useful to monitor cardiac function in this cohort of patients for the dur. Tag Archives: NF-1 strain review. 2 (). Main Effects of NF1. NF1 is an uridine auxotroph derived from the strain TK3 which is used in food fermentation (Doumas et al. The uplifting, energetic buzz is one you. Get details and read the latest customer reviews about NF-1 by Northern Emeralds on Leafly. The strain has garnered almost as much publicity as it has nicknames; as well as GMO, it is known as Garlic Cookies and GMO Cookies. A. Heredity and variation are inherent characteristics of species and are mainly reflected in the stability and variation of the genome; the former is relative, while the latter is continuous. Opens in new window. Consumers who have smoked this. comNf-1 by “Up North” Ill start by saying I don’t normally buy hybrids but this one stood out. This batch of flower tested at 0. hydrophila; the NF1 strain itself itself holds the antidote to. When using the Nf1 Fcr mouse strain in a publication, please cite the originating article(s) and include JAX stock #002646 in your Materials and Methods section. Sage. If you've smoked this. Preliminary anchoring of scaffolds using a 37 pseudo-molecules reference (NF_TY) during the assembly process, genes can be positioned onto 37 newly assembled pseudo. 58. 10%. B6. Male, 1978-03-29, Amsterdam, Dutch. Third, Tsc1 inactivation in neuroglial progenitor. It is caused by a mutation in the NF1 gene. Its population prevalence is approximately 1 in 3000. If you are a regular cannabis user, there is a very high probability that you have tried either Northern Lights or Chemdawg strain. 1–5 The types of tumors encountered in children and adults with NF1 differ in terms of brain location, age at presentation, and clinical behavior. It is named after a genetic disorder that causes benign growths in the eye, skin, and head. Lucid Blue is a supremely potent sativa that will bring your thoughts to a new level of consciousness. fowleri (NF_NF1 strain, blue) can be connected with those of N. oryzae strains and expression plasmid. 707-630-5179. Strain Name: C57BL/6JGpt-Nf1 em39Cd7411in2 /Gpt: Strain Number: T012162: Official Symbol: Nf1: Strain Strategy: T012162. Homozygous embryos do not survive beyond E12. Delivery Dispensaries Deals Strains Brands Products CBD Doctors Cannabis 101 Social impact. Opens in new window. Although its exact parentage is kept a closely guarded secret by its breeders, F1 is often sought out for its super high level of potency and giddy daytime effects that make for the perfect. Patients with NF1 treated with selumetinib may experience subtle changes in systolic function identified by global longitudinal strain and not revealed by left ventricular ejection fraction. In a world. When the strains occur together, the story is reversed. com and find the best Marijuana dispensaries in cities like Boston, Worcester, Springfield, Lowell, Cambridge and many more. NF-1 is an indica-leaning hybrid cross of Northern Lights and Chemdawg. The NF1 patient c. NF-1 by UpNorth (Aeriz), havent seen anything in the sub about it so figured id post. UpNorth NF-1. Our Cultivate Premium line is always hand. breeders, many have laid claim to this strain’s creation. Each child of an affected. An earlier report described a human case of necrotizing fasciitis (NF) caused by mixed infection with 4 Aeromonas hydrophila strains (NF1-NF4). 6 than from it's closest relatives, meaning that the horizontal transfer was directed from the fuscans lineage. Neurofibromatosis type 1 (NF1), which accounts for about 90% of all cases of neurofibromatosis. NF1 strain was determined to be phylogenetically distinct and exhibited contact-dependent killing of NF2 mediated by T6SS at 37°C . What is NF1 strain. We're still learning about the flavors and effects of NF1. A strain specific cannabis extract. Mitochondrial. It is perfect for treating conditions such as chronic pain, depression, nausea and PTSD. Category: Flower NF1 Strain Lineage: Northern Lights x Chemdawg Description: NF1 Strain is a hybrid with some very well-known parents—Northern Lights and Chemdawg. Significance Necrotizing fasciitis (NF) is a rapidly progressing fatal skin and muscle tissue lesion. . . This grower used our clones: Blueberry Green Crack, Blue Dream, Sour Diesel and Durban. Neurofibromatosis type 1 (NF1), one of the most common autosomal dominant genetic disorders, is caused by mutations in the NF1 gene. 1994 Jul;7(3):353-61. Get details and read the latest customer reviews about NF1 by Commonwealth Alternative Care (CAC) on Leafly. MGI:3775645. Best known for its super delicious flavor, Wedding Mints #11 packs a soothing, well-balanced high and a great taste into each and every toke. Espresso Strain. Neurofibromatosis type 1 (NF1) is one of the most common genetic tumor predisposition syndrome, caused by mutations in the NF1 . With a balanced, mellow high and a universally appealing flavor profile, this is a great strain for social use. Nf1 gene expression in mouse strains with differences in tumor susceptibility using quantitative polymerase chain reaction. NF-1 is a cross of two famous strains Northern Lights x Chemdawg from Upnorth Humboldt (Aeriz). Humans with mutations in NF1 develop neurofibromatosis type I (NF1) and have increased risk of optic gliomas, astrocytomas and glioblastomas. The NF1 strain often gets labeled as a Sativa-dominant hybrid thanks to its roots. An earlier report described a human case of necrotizing fasciitis (NF) caused by mixed infection with 4 Aeromonas hydrophila strains (NF1–NF4). I got one nug thats 3. 5 Grams | Genetics: Chemdawg x Northern Lights | If you are a regular cannabis user, there is a very high probability that you have tried either Northern. When the strains occur together, the story is reversed. They are suitable for use in applications related to the study of neurofibromatosis type. NF1 - Indica Hybrid - by UpNorth Cannabis - Strain Review - from Buds & Roses, Studio City CaWeedEntertainment. Strain Gene Model ID Feature Type Coordinates Select Strains; C57BL/6J: MGI_C57BL6J_97306: protein coding gene: Chr11:79223541-79472438 (+) 129S1/SvImJ:. For each strain, we've documented its history, genetic background, appearance, aroma, unique qualities and flavor. NF1 is a hybrid with some very well-known parents—Northern Lights and Chemdawg. NF1 happens in about 1 in 3,000 births. While the NF2, NF3, and NF4 strains were clonal and possessed exotoxin A (ExoA), the NF1 strain was determined to be phylogenetically distinct, harboring a unique type 6 secretion system. Thankfully, these two heavy indica strains of medical cannabis for neurofibromatosis are excellent for getting you off to sleep: Northern Lights.